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Cayman BTS
List Price
$462.00
Your Price
$462.00
Cayman BTS - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-30099-25
MFG.PART:
30099-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
BTS is an inhibitor of skeletal muscle myosin II ATPase activity that reduces the affinity of ADP-myosin for actin.1 It inhibits calcium-stimulated ATPase activity of rabbit muscle myosin subfragment 1 (S1) in an actin-independent manner with an IC50 value of approximately 5 µM. It is selective for calcium-stimulated myosin II over human platelet myosin II, kinesin, pyruvate kinase, and lactate dehydrogenase at 100 µM. BTS (2 µM) inhibits the activity of skeletal muscle myosin, reversibly reducing the sliding velocity of heavy meromyosin in a gliding-filament assay. It inhibits isometric calcium-activated tension in isolated fast-twitch rabbit psoas muscle fibers (IC50 = ~3 µM) but not in isolated slow-twitch rat trabeculae and papillary cardiac muscle. BTS is also an intermediate in the synthesis of sulfonamides.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-methyl-N-
CAS Number
1576-37-0
Synonyms
- N-Benzyl-p-toluenesulfonamide
- NSC 37123
Molecular Formula
C14H15NO2S
Formula Weight
261.3
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 10 mg/mL
- DMSO: 20 mg/mL
- DMSO:PBS (pH 7.2) (1:4): 0.2 mg/mL
- Ethanol: 5 mg/mL
λmax
229 nm
SMILES
CC1=CC=C(S(NCC2=CC=CC=C2)(=O)=O)C=C1
InChi Code
InChI=1S/C14H15NO2S/c1-12-7-9-14(10-8-12)18(16,17)15-11-13-5-3-2-4-6-13/h2-10,15H,11H2,1H3
InChi Key
WTHKAJZQYNKTCJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30099-25 |
|---|---|
| Supplier Part Number | 30099-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 1576-37-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |