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Cayman Isoconazole (Nitrate)
List Price
$172.00
Your Price
$172.00
Cayman Isoconazole (Nitrate) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-30100-5
MFG.PART:
30100-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Isoconazole is an imidazole with antimicrobial activity.1 It is active against clinical isolates of Candida species, including C. albicans, C. parapsilosis, C. tropicalis, C. krusei, and C. guilliermondii with MIC values ranging from 0.12 to 2 μg/ml. It is also active against the fungi T. mentagrophytes and T. rubrum when used at a concentration of 0.1 µg/ml and the bacteria C. tuberculostearicum, methicillin-resistant S. aureus (MRSA), and S. epidermis (MICs = 3.9, 32, and 5.6 mg/L, respectively).2,3 Isoconazole induces the production of reactive oxygen species (ROS) in S. aureus.3 It also inhibits heme oxygenase in rat spleen and rat brain microsomes that endogenously express high levels of heme oxygenase-1 (HO-1) and HO-2, respectively (IC50s = 5.6 and 32.6 µM, respectively).4
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-[2-(2,4-
CAS Number
24168-96-5
Synonyms
- Adestan G 100
- R 15454
Molecular Formula
C18H14Cl4N2O • HNO3
Formula Weight
479.1
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 10mg/mL
- DMF:PBS (pH 7.2) (1:4): 0.2mg/mL
- DMSO: 10mg/mL
SMILES
ClC1=CC=CC(Cl)=C1COC(C2=C(Cl)C=C(Cl)C=C2)CN3C=CN=C3.[O-][N+](O)=O
InChi Code
InChI=1S/C18H14Cl4N2O.HNO3/c19-12-4-5-13(17(22)8-12)18(9-24-7-6-23-11-24)25-10-14-15(20)2-1-3-16(14)21;2-1(3)4/h1-8,11,18H,9-10H2;(H,2,3,4)
InChi Key
NNGQLSIGRSTLLU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30100-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 30100-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 24168-96-5 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |