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Cayman CAY10753
List Price $461.00 Your Price $461.00
Cayman CAY10753 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-30277-10
MFG.PART: 30277-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
CAY10753 is an inhibitor of tankyrase 2 (TNKS2; IC50 = 0.3 nM).1 It is selective for TNKS2 over TNKS1 (IC50 = 6.1 nM), as well as poly(ADP-ribose) polymerase 1 (PARP1) and PARP2 (IC50s = 89.6 and 37.8 nM, respectively). CAY10753 inhibits proliferation of DLD-1 colorectal cancer cells when used at a concentration of 1 µM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2,2-
Molecular Formula
C24H26N6O2S2
Formula Weight
494.6
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMSO: slightly soluble
- Methanol: slightly soluble
λmax
230, 273 nm
SMILES
O=C1NC(SCCN2CCN(CCSC(N3)=NC4=C(C=CC=C4)C3=O)CC2)=NC5=C1C=CC=C5
InChi Code
InChI=1S/C24H26N6O2S2/c31-21-17-5-1-3-7-19(17)25-23(27-21)33-15-13-29-9-11-30(12-10-29)14-16-34-24-26-20-8-4-2-6-18(20)22(32)28-24/h1-8H,9-16H2,(H,25,27,31)(H,26,28,32)
InChi Key
RHCZTJJJLXGIDT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-30277-10 |
|---|---|
| Supplier Part Number | 30277-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |