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Cayman YL-109
List Price $388.00 Your Price $388.00
Cayman YL-109 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-30290-25
MFG.PART: 30290-25
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
YL-109 is an anticancer agent.1 It inhibits the proliferation of MCF-7 and MDA-MB-231 cells (IC50s = 0.0858 and 4.2 µM, respectively), as well as migration and invasion by MDA-MB-231 cells in vitro. It induces expression of carboxyl terminus of Hsp70-interacting protein (CHIP) in MDA-MB-231 cells in an AHR-dependent manner. YL-109 (1 µM) inhibits MDA-MB-231-derived cancer stem cell (CSC) mammosphere formation. In vivo, YL-109 (15 mg/kg) reduces tumor volume and the number of metastases in an MDA-MB-231 mouse xenograft model.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-(2-benzo
CAS Number
36341-25-0
Molecular Formula
C14H11NO2S
Formula Weight
257.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS (pH 7.2) (1:9): 0.1 mg/mL
- Ethanol: 1 mg/mL
λmax
220, 327 nm
SMILES
COC1=CC(C2=NC3=CC=CC=C3S2)=CC=C1O
InChi Code
InChI=1S/C14H11NO2S/c1-17-12-8-9(6-7-11(12)16)14-15-10-4-2-3-5-13(10)18-14/h2-8,16H,1H3
InChi Key
KRVBOHJNAFQFPW-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30290-25 |
|---|---|
| Supplier Part Number | 30290-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 36341-25-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |