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Cayman AZ9482
List Price $736.00 Your Price $736.00
Cayman AZ9482 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-30292-25
MFG.PART: 30292-25
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
AZ9482 is a poly(ADP-ribose) polymerase (PARP) inhibitor (IC50s = 1, 1, 46, 640, 9, and 160 nM for PARP1, -2, -3, -6, TNKS1/PARP5a, and TNKS2, respectively).1 It induces centrosome declustering (EC50 = <18 nM) and a multipolar spindle phenotype in HeLa cells. AZ9482 inhibits the growth of OCI-LY19 diffuse large B cell lymphoma (DLBCL) cells (GI50 = 3 nM).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[4-[3-[(3,4-
CAS Number
1825345-33-2
Molecular Formula
C26H22N6O2
Formula Weight
450.5
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 0.25mg/mL
- DMSO: 0.15mg/mL
λmax
265 nm
SMILES
O=C1C2=CC=CC=C2C(CC3=CC(C(N4CCN(C5=NC=CC=C5C#N)CC4)=O)=CC=C3)=NN1
InChi Code
InChI=1S/C26H22N6O2/c27-17-20-7-4-10-28-24(20)31-11-13-32(14-12-31)26(34)19-6-3-5-18(15-19)16-23-21-8-1-2-9-22(21)25(33)30-29-23/h1-10,15H,11-14,16H2,(H,30,33)
InChi Key
ZDDPBFWHZOJFHF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30292-25 |
|---|---|
| Supplier Part Number | 30292-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1825345-33-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |