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Cayman BSH-IN-1
List Price $102.00 Your Price $102.00
Cayman BSH-IN-1 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-30311-1
MFG.PART: 30311-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
BSH-IN-1 is a covalent inhibitor of bile salt hydrolases. It is selective for bile salt hydrolases over the farnesoid X receptor (FXR) and g protein-coupled bile acid activated receptor (GP-bar) at 100 µM. BSH-IN-1 inhibits the bile salt hydrolases of the Gram-negative bacterium B. theta and the Gram-positive bacterium B. longum (IC50s = 427 and 108 nM, respectively). It also inhibits deconjugation of bile acids in a variety of bacteria and in resuspended mouse feces. Oral administration of BSH-IN-1 (10 mg/kg) decreases bile salt hydrolase activity and deconjugated bile acid levels in feces in mice.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(R)-5-((3R,5S,
CAS Number
2553217-91-5
Molecular Formula
C25H41FO3
Formula Weight
408.6
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: 10 mm
SMILES
FCC(CC[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C)=O
InChi Code
InChI=1S/C25H41FO3/c1-15(4-5-18(28)14-26)19-6-7-20-23-21(9-11-25(19,20)3)24(2)10-8-17(27)12-16(24)13-22(23)29/h15-17,19-23,27,29H,4-14H2,1-3H3/t15-,16+,17-,19-,20+,21+,22-,23+,24+,25-/m1/s1
InChi Key
XDVGNIBMZHDZLL-GDQMVUAZSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30311-1 |
|---|---|
| Supplier Part Number | 30311-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2553217-91-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |