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Cayman WM-1119
List Price $215.00 Your Price $215.00
Cayman WM-1119 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-30509-10
MFG.PART: 30509-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
WM-1119 is an orally bioavailable inhibitor of lysine acetyltransferase 6A (KAT6A/MOZ; IC50 = 6.3 nM). It binds to KAT6A with a Kd value of 2 nM and is selective for KAT6A over KAT5 and KAT7 (Kds = 2,200 and 500 nM, respectively), as well as over a panel of 159 additional targets at 1 and 10 μM. WM-1119 inhibits proliferation of EMRK1184 B cell lymphoma cells (IC50 = 0.25 μM). It reduces tumor growth and spleen weight in a murine EMRK1184 model when administered at a dose of 50 mg/kg four times per day.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-fluoro-5-
CAS Number
2055397-28-7
Molecular Formula
C18H13F2N3O3S
Formula Weight
389.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS (pH 7.2) (1:4): 0.25 mg/mL
λmax
223, 277 nm
SMILES
FC1=CC(C(NNS(C2=C(F)C=CC=C2)(=O)=O)=O)=CC(C3=NC=CC=C3)=C1
InChi Code
InChI=1S/C18H13F2N3O3S/c19-14-10-12(16-6-3-4-8-21-16)9-13(11-14)18(24)22-23-27(25,26)17-7-2-1-5-15(17)20/h1-11,23H,(H,22,24)
InChi Key
QLXULUNLCRKWRD-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30509-10 |
|---|---|
| Supplier Part Number | 30509-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2055397-28-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |