We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Cayman Para-Methyl Ap-237 (Hydrochloride), (E)-1-(4-(3-(P-Tolyl)A
List Price
$356.00
Your Price
$356.00
Cayman Para-Methyl Ap-237 (Hydrochloride), (E)-1-(4-(3-(P-Tolyl)Allyl)Piperazin-1-Yl)Butan-1-One, Monohydrochloride, 5 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-30744-5
MFG.PART:
30744-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
NU 6140 is a cyclin-dependent kinase 2 (Cdk2) inhibitor (IC50 = 0.41 μM) that demonstrates 10- to 36-fold selectivity against Cdk2-cyclin A compared to Cdk1-cyclin B, Cdk4-cyclin D, Cdk5-p25, or Cdk7-cyclin H. NU 6140 has been found to induce cell-cycle arrest at the G2-M phase and to potentiate the apoptotic effect of paclitaxel (Item No. ) in HeLa cells by inhibiting the anti-apoptotic protein, survivin.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[[6-(cyclo
CAS Number
444723-13-1
Molecular Formula
C23H30N6O2
Formula Weight
422.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
- Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
λmax
307 nm
SMILES
O=C(N(CC)CC)C1=CC=C(NC2=NC(OCC3CCCCC3)=C(NC=N4)C4=N2)C=C1
InChi Code
InChI=1S/C23H30N6O2/c1-3-29(4-2)22(30)17-10-12-18(13-11-17)26-23-27-20-19(24-15-25-20)21(28-23)31-14-16-8-6-5-7-9-16/h10-13,15-16H,3-9,14H2,1-2H3,(H2,24,25,26,27,28)
InChi Key
XHEQSRJCJTWWAH-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30744-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 30744-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |