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Cayman Valganciclovir-D5 (Hydrochloride), Dl-Valine, 2-[(2-Amino-
List Price
$283.00
Your Price
$283.00
Cayman Valganciclovir-D5 (Hydrochloride), Dl-Valine, 2-[(2-Amino-1,6-Dihydro-6-Oxo-9h-Purin-9-Yl)Methoxy]-3-Hydroxypropyl-1,1,2,3,3-D5 Ester, Monohydrochloride, 1 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-30746-1
MFG.PART:
30746-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Tenapanor is an orally bioavailable inhibitor of sodium-hydrogen exchanger 3 (NHE-3; IC50 = 10 nM for the recombinant rat protein). Tenapanor (10 µM) inhibits intestinal fluid absorption in mouse jejunum, but not distal colon, in a closed intestine loop assay. It also lowers both the sodium and phosphate urinary-to-dietary ratio in a dose-dependent manner in rats. Tenapanor (5 mg/kg) reverses decreases in stool pellet numbers and water content induced by loperamide (Item No. ) and prevents loperamide-induced constipation in mice. Formulations containing tenapanor have been used in the treatment of irritable bowel syndrome with constipation.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
17-[[[3-[(4S)-
CAS Number
1234365-97-9
Synonyms
- AZD 1722
Molecular Formula
C50H66Cl4N8O10S2 • 2HCl
Formula Weight
1218.0
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMSO: Soluble
- Water: Soluble
SMILES
O=S(NCCOCCOCCNC(NCCCCNC(NCCOCCOCCNS(=O)(C1=CC=CC([C@@]2(CN(C)CC3=C(Cl)C=C(C=C23)Cl)[H])=C1)=O)=O)=O)(C4=CC([C@@]5([H])C6=CC(Cl)=CC(Cl)=C6CN(C5)C)=CC=C4)=O.Cl.Cl
InChi Code
InChI=1S/C50H66Cl4N8O10S2.2ClH/c1-61-31-43(41-27-37(51)29-47(53)45(41)33-61)35-7-5-9-39(25-35)73(65,66)59-15-19-71-23-21-69-17-13-57-49(63)55-11-3-4-12-56-50(64)58-14-18-70-22-24-72-20-16-60-74(67,68)40-10-6-8-36(26-40)44-32-62(2)34-46-42(44)28-38(52)30-48(46)54;;/h5-10,25-30,43-44,59-60H,3-4,11-24,31-34H2,1-2H3,(H2,55,57,63)(H2,56,58,64);2*1H/t43-,44-;;/m0../s1
InChi Key
VFRAXTZDILCRKY-OWRGXFNZSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30746-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 30746-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |