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Cayman Cbnq
Product Description
C6 NBD sphingomyelin is a biologically active derivative of sphingomyelin (Item Nos. | ) that is tagged with a fluorescent C6 nitrobenzoxadiazole (C6 NBD; Item No. ) group. C6 NBD sphingomyelin has been used to study the metabolism and transport of sphingomyelins., It is degraded in the plasma membrane to C6 NBD ceramide (Item No. ) by neutral sphingomyelinase, an enzyme with three-fold higher activity in undifferentiated HT29 cells than in differentiated cells. Unlike endogenous long-chain sphingomyelin and C6 sphingomyelin, C6 NBD sphingomyelin can be transported to the cell surface even in the presence of the vesicular transport inhibitor brefeldin A (Item No. ), but this transport can be blocked by multidrug resistance protein inhibitors in CHO cells. This product is a mixture of the D-erythro and L-threo isomers of sphingomyelin. As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1912]
WARNING This product is not for human or veterinary use.
Technical Information
- N-hexanoyl-NBD Sphingosylphosphorylcholine
- NBD SM(d18:1/6:0)
- NBD Sphingomyelin (d18:1/6:0)
- Chloroform: Soluble
- Ethanol: Soluble
- Methanol: Soluble
Shipping & Storage Information
| SKU | CAYM-30863-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 30863-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 731773-46-9 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |