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Cayman Cu-CPT4a
List Price $75.00 Your Price $75.00
Cayman Cu-CPT4a - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-30951-500
MFG.PART: 30951-500
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Cu-CPT4a is a toll-like receptor 3 (TLR3) antagonist (IC50 = 3.44 µM).1 It is selective for TLR3 over TLR4, TLR2/6, TLR1/2, and TLR7 at 27 µM. Cu-CPT4a inhibits dsRNA binding to TLR3 with a Ki value of 2.96 µM in a fluorescence anisotropy assay. It decreases poly(I:C)-induced production of TNF-α and IL-1β in RAW 264.7 cells when used at a concentration of 27 µM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[(3-chloro-
CAS Number
1279713-77-7
Molecular Formula
C18H13ClFNO3S
Formula Weight
377.8
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMSO: 100 mm
SMILES
FC1=CC=C(C(Cl)=C(C(N[C@H](CC2=CC=CC=C2)C(O)=O)=O)S3)C3=C1
InChi Code
InChI=1S/C18H13ClFNO3S/c19-15-12-7-6-11(20)9-14(12)25-16(15)17(22)21-13(18(23)24)8-10-4-2-1-3-5-10/h1-7,9,13H,8H2,(H,21,22)(H,23,24)/t13-/m1/s1
InChi Key
IAASQMCXDRISAV-CYBMUJFWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30951-500 |
|---|---|
| Supplier Part Number | 30951-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1279713-77-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |