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Cayman N106
List Price $283.00 Your Price $283.00
Cayman N106 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-30952-10
MFG.PART: 30952-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
N106 is an activator of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase 2A (SERCA2A) SUMOylation.1 It activates SUMO-activating enzyme E1, which increases SUMOylation and the activity of SERCA2A in isolated adult rat cardiomyocytes when used at concentrations ranging from 0.1 to 1 µM. N106 increases contractility in the same cells. In vivo, N106 (10 mg/kg) increases cardiac SERCA2A SUMOylation and contractility in a mouse model of pressure overload-induced heart failure.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-methoxy-N-
CAS Number
862974-25-2
Molecular Formula
C17H14N4O3S
Formula Weight
354.4
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMSO: 20 mg/mL
SMILES
COC1=C(N=C(NC2=NN=C(C3=CC=C(OC)C=C3)O2)S4)C4=CC=C1COC1=C(N=C(NC2=NN=C(C3=CC=C(OC)C=C3)O2)S4)C4=CC=C1
InChi Code
InChI=1S/C17H14N4O3S/c1-22-11-8-6-10(7-9-11)15-20-21-16(24-15)19-17-18-14-12(23-2)4-3-5-13(14)25-17/h3-9H,1-2H3,(H,18,19,21)
InChi Key
FBCSWQRNKAYAGY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30952-10 |
|---|---|
| Supplier Part Number | 30952-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 862974-25-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |