We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Cayman TGN 020
List Price
$95.00
Your Price
$95.00
Cayman TGN 020 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-30955-10
MFG.PART:
30955-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
TGN 020 is an aquaporin-4 (AQP4) inhibitor (IC50 = 3.1 μM in X. laevis oocytes transfected with AQP4). It reduces brain edema and cortical infarction size in a mouse model of transient focal cerebral ischemia induced by middle cerebral artery occlusion (MCAO) when administered at a dose of 200 mg/kg. TGN 020 (200 mg/kg every 6 hours) reduces bronchoalveolar lavage fluid (BALF) IL-1α, IL-1β, IL-6, TNF-α, IL-23, and IL-17A levels and neutrophil infiltration, as well as increases survival, in a mouse model of LPS-induced acute lung injury.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-1,3,4-
CAS Number
51987-99-6
Molecular Formula
C8H6N4OS
Formula Weight
206.2
Purity
≥98%
Formulation
A solid
Solubility
- DMF: 100µg/mL
- DMSO: 2 mg/mL
- DMSO:PBS (pH 7.2) (1:9): 100µg/mL
- Ethanol: 100µg/mL
λmax
220, 268 nm
SMILES
O=C(NC1=NN=CS1)C2=CN=CC=C2
InChi Code
InChI=1S/C8H6N4OS/c13-7(6-2-1-3-9-4-6)11-8-12-10-5-14-8/h1-5H,(H,11,12,13)
InChi Key
AGEGZHOPKZFKBP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30955-10 |
|---|---|
| Supplier Part Number | 30955-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 51987-99-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |