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Cayman YS-49
List Price
$54.00
Your Price
$54.00
Cayman YS-49 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-30970-1
MFG.PART:
30970-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
YS-49 is an inhibitor of platelet aggregation. It inhibits ADP-, collagen-, or epinephrine-induced platelet aggregation in isolated human platelets (IC50s = 730, 92, and 3.4 µM, respectively). YS-49 also inhibits platelet aggregation and production of thromboxane A2 (TXA2) induced by arachidonic acid (Item Nos. | | ) in isolated rat platelets (IC50s = 3.3 and 32.8 µM, respectively). It reduces LPS-induced contractions in isolated endothelium-denuded rat aortic strips in a concentration-dependent manner. YS-49 (50 mg/kg) decreases thrombus weight in a rat model of arterio-venous shunt thrombosis. It increases survival in a mouse model of septicemia induced by LPS when administered at doses of 10 and 20 mg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1,2,3,4-tetra
CAS Number
132836-42-1
Molecular Formula
C20H19NO2 • HBr
Formula Weight
386.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
- Ethanol:PBS (pH 7.2) (1:2): 0.33 mg/mL
λmax
225 nm
SMILES
OC1=C(O)C=C(CCNC2CC3=C(C=CC=C4)C4=CC=C3)C2=C1.Br
InChi Code
InChI=1S/C20H19NO2.BrH/c22-19-11-15-8-9-21-18(17(15)12-20(19)23)10-14-6-3-5-13-4-1-2-7-16(13)14;/h1-7,11-12,18,21-23H,8-10H2;1H
InChi Key
JXFRKNGQHAAJKY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-30970-1 |
|---|---|
| Supplier Part Number | 30970-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 132836-42-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |