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Cayman Buflomedil (hydrochloride)
List Price $173.00 Your Price $173.00
Cayman Buflomedil (hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-31184-10
MFG.PART: 31184-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Buflomedil is a non-selective antagonist of α-adrenergic receptors (α-ARs) and vasoactive compound.,,, It binds to rat α1A- and α1B-ARs (Kis = 4.06 and 6.84 µM, respectively) and human platelet α2-ARs (IC50 = 1 µM) in radioligand binding assays., Buflomedil (0.06-60 µM) inhibits contraction of isolated canine saphenous veins induced by phenylephrine, clonidine (Item No. ), sympathetic nerve stimulation, or norepinephrine. It inhibits ADP-, collagen-, or epinephrine-induced aggregation of isolated human platelets when used at a concentration of 100 µM. Buflomedil (10 mg/kg) reduces hippocampal neuronal cell death in a rat model of carotid clamping-induced ischemia-reperfusion injury.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-(1-pyrro
CAS Number
35543-24-9
Synonyms
- LL-1656
Molecular Formula
C17H25NO4 • HCl
Formula Weight
343.9
Purity
≥95%
Formulation
A solid
Solubility
- DMF: 3mg/mL
- DMSO: 2mg/mL
- Ethanol: 3mg/mL
- PBS (pH 7.2): 10mg/mL
SMILES
COC1=CC(OC)=C(C(CCCN2CCCC2)=O)C(OC)=C1.Cl
InChi Code
InChI=1S/C17H25NO4.ClH/c1-20-13-11-15(21-2)17(16(12-13)22-3)14(19)7-6-10-18-8-4-5-9-18;/h11-12H,4-10H2,1-3H3;1H
InChi Key
ZDPACSAHMZADFZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-31184-10 |
|---|---|
| Supplier Part Number | 31184-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 35543-24-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |