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Cayman D-Serine
List Price $158.00 Your Price $158.00
Cayman D-Serine - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-31197-50
MFG.PART: 31197-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
D-Serine is the dextrorotary isomer of the non-essential amino acid L-serine and a co-agonist of NMDA receptors.1 It is formed by conversion of L-serine by serine racemase and found primarily in the brain.2,3 D-Serine binds to the glycine site of the NMDA receptor and potentiates glutamate-induced currents in oocytes expressing various subunit combinations (EC50s = 0.17-0.32 µM) more potently than glycine.1,3 It reverses deficits in prepulse inhibition with prepulses of 69 and 73 decibels (dB), but not 81 dB, and increases the time spent in the target quadrant of the Morris water maze in mice with a mutant form of serine racemase (SrrY269*) when administered at a dose of 600 mg/kg.4 Serum levels of D-serine are decreased in patients with schizophrenia.5
WARNING This product is not for human or veterinary use.
Technical Information
CAS Number
312-84-5
Synonyms
- NSC 77689
- (R)-Serine
Molecular Formula
C3H7NO3
Formula Weight
105.1
Purity
≥95%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- PBS (pH 7.2): 5 mg/mL
SMILES
OC[C@@H](N)C(O)=O
InChi Code
InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1
InChi Key
MTCFGRXMJLQNBG-UWTATZPHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-31197-50 |
|---|---|
| Supplier Part Number | 31197-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 312-84-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |