Cayman Isovitexin

Isovitexin is a C-glycosylated flavone that has been found in Patrinia villosa and has diverse biological activities.^,,,, It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. ) radicals in a cell-free assay (IC₅₀ = 370 µg/mL). Isovitexin (50 and 100 µg/mL) is cytotoxic to HepG2 hepatic, MCF-7 breast, and HCT116 colorectal cancer cells. It inhibits LPS-induced production of TNF-α and IL-6 and decreases inducible nitric oxide synthase (iNOS) and COX-2 levels in RAW 264.7 cells when used at a concentration of 50 µg/mL. Isovitexin (200 µg/mL) reduces cytotoxicity induced by amyloid-β (25-35) (Aβ (25-35)) in PC12 cells.

WARNING This product is not for human or veterinary use.