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Cayman CLP 290
List Price
$106.00
Your Price
$106.00
Cayman CLP 290 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-31448-5
MFG.PART:
31448-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
CLP 290 is a carbamate prodrug form of the K+/Cl- cotransporter 2 (KCC2) activator CLP 257 (Item No. 30948).1 It increases the mechanical paw withdrawal threshold in a rat model of peripheral nerve injury and reverses morphine-induced hyperalgesia in rats when administered at a dose of 100 mg/kg.1,2 CLP 290 (35 mg/kg) also restores stepping ability, as well as increases body weight support and stride length, in a mouse model of paralysis induced by staggered spinal lesions.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-pyrrolidine
CAS Number
1181083-81-7
Molecular Formula
C19H21FN4O3S
Formula Weight
404.5
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 1 mg/mL
- DMSO: 1 mg/mL
- DMSO:PBS (pH 7.2) (1:6): 0.14 mg/mL
λmax
243, 336 nm
SMILES
O=C(N1CCCC1)OC(C=C(C=C2)F)=C2/C=C3SC(N4CCCCN4)=NC\3=O
InChi Code
InChI=1S/C19H21FN4O3S/c20-14-6-5-13(15(12-14)27-19(26)23-8-3-4-9-23)11-16-17(25)22-18(28-16)24-10-2-1-7-21-24/h5-6,11-12,21H,1-4,7-10H2/b16-11-
InChi Key
DIXMMXNNKLCLOM-WJDWOHSUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-31448-5 |
|---|---|
| Supplier Part Number | 31448-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1181083-81-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |