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Cayman Famotidine-13c-D3, 3-[[[2--4-Thia
List Price
$522.00
Your Price
$522.00
Cayman Famotidine-13c-D3, 3-[[[2-[(Aminoiminomethyl)Amino]-4-Thiazolyl]Methyl]Thio]-N-(Aminosulfonyl)-Propanimidamide1-13c-2,3,3-D3, 1 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-31493-1
MFG.PART:
31493-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Akt inhibitor IV is an inhibitor of Akt activation that inhibits Akt-mediated nuclear export of Forkhead box class O transcription factor 1a (FOXO1a; IC50 = 625 nM) and reduces phosphorylation of Akt at Ser473 and Thr308 in a dose-dependent manner. Akt inhibitor IV inhibits replication of parainfluenza virus 5 (PIV5) in HeLa cells (IC50 = 520 nM). It also reduces the growth of cancer cells (IC50 = 0.3 μM for both Jurkat and HeLa cells) via a reduction in mitochondrial polarization and increased production of reactive oxygen species (ROS).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
6-(2-benzothia
CAS Number
681281-88-9
Molecular Formula
C31H27N4S • I
Formula Weight
614.6
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
λmax
386 nm
SMILES
CC[N+]1=C(/C=C/N(C2=CC=CC=C2)C)N(C3=CC=CC=C3)C4=CC=C(C5=NC(C=CC=C6)=C6S5)C=C41.[I-]
InChi Code
InChI=1S/C31H27N4S.HI/c1-3-34-28-22-23(31-32-26-16-10-11-17-29(26)36-31)18-19-27(28)35(25-14-8-5-9-15-25)30(34)20-21-33(2)24-12-6-4-7-13-24;/h4-22H,3H2,1-2H3;1H/q+1;/p-1
InChi Key
NAYRELMNTQSBIN-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-31493-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 31493-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |