We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Cayman QD-394
List Price $250.00 Your Price $250.00
Cayman QD-394 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-31769-5
MFG.PART: 31769-5
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
QD-394 is an inducer of reactive oxygen species (ROS) production.1 It induces lipid peroxidation, increases in intracellular accumulation of reactive oxygen species (ROS), and decreases in the reduced glutathione (GSH) to oxidized GSH (GSSG) ratio in MIA PaCa-2 pancreatic cancer cells when used at concentrations ranging from 0.5 to 10 µM. QD-394 is cytotoxic to MIA PaCa-2, PANC-1, and BxPC-3 cancer cells (IC50s = 0.64, 0.34, and 0.9 µM, respectively). QD-394 acts synergistically with napabucasin (Item No. 22255) to reduce colony formation in MIA PaCa-2 cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
6-[[4-(4-
CAS Number
2132411-21-1
Molecular Formula
C19H19N5O2
Formula Weight
349.4
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 1 mg/lm
- DMSO: 5 mg/mL
- DMSO:PBS (pH 7.2) (1:20): 0.04 mg/mL
- Ethanol: 1 mg/lm
- PBS (pH 7.2): slightly soluble
λmax
271 nm
SMILES
O=C1C=C(C(C2=CN=CN=C12)=O)NC3=CC=C(N4CCN(CC4)C)C=C3
InChi Code
InChI=1S/C19H19N5O2/c1-23-6-8-24(9-7-23)14-4-2-13(3-5-14)22-16-10-17(25)18-15(19(16)26)11-20-12-21-18/h2-5,10-12,22H,6-9H2,1H3
InChi Key
INZGOHBCPALCGM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-31769-5 |
|---|---|
| Supplier Part Number | 31769-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2132411-21-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |