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Cayman NR-160
List Price
$90.00
Your Price
$90.00
Cayman NR-160 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-31792-1
MFG.PART:
31792-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
NR-160 is an inhibitor of histone deacetylase 6 (HDAC6; IC50 = 0.03 µM). It is selective for HDAC6 over HDAC1, -2, -3, -4, and -8 (IC50s = 5.18, 2.26, 8.48, 55.4, and 14.7 µM, respectively). NR-160 is cytotoxic against a panel of seven cancer cell lines (IC50s = 22.5-51.8 µM). It enhances cytotoxicity induced by bortezomib (Item No. ) in HL-60 cells, as well as cytotoxicity induced by epirubicin (Item No. ) or daunorubicin (Item No. ) in CCRF-HSB-2 T cell acute lymphoblastic leukemia cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[[4-[(hydroxy
CAS Number
2484895-50-1
Molecular Formula
C25H21F3N6O3
Formula Weight
510.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 1 mg/mL
SMILES
O=C(NO)C(C=C1)=CC=C1CN(CC2=NN=NN2CC3=CC=CC=C3)C(C4=C(C(F)(F)F)C=CC=C4)=O
InChi Code
InChI=1S/C25H21F3N6O3/c26-25(27,28)21-9-5-4-8-20(21)24(36)33(14-18-10-12-19(13-11-18)23(35)30-37)16-22-29-31-32-34(22)15-17-6-2-1-3-7-17/h1-13,37H,14-16H2,(H,30,35)
InChi Key
MEWDNULKAXEKII-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-31792-1 |
|---|---|
| Supplier Part Number | 31792-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2484895-50-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |