Cayman α-Tubulin Monoclonal Antibody (RM113)

α-Tubulin is a cytoskeletal protein and constituent of microtubules, a cytoskeletal assembly that has roles in a variety of cellular processes, including cell motility, division, differentiation, and intracellular transport. α-Tubulin is highly conserved in eukaryotes and expressed in a cell- and isotype-specific manner. There are eight human α-tubulin isotypes that consist of an N-terminal domain, which binds GTP and is required for microtubule self-assembly, and a variable C-terminal tail, which contains interaction sites for microtubule-associated proteins (MAPs) and is subject to a variety of post-translational modifications that regulate microtubule function and stability.^,,, Caymans α-Tubulin Monoclonal Antibody (RM113) can be used for immunocytochemistry (ICC) and Western blot (WB) applications. The antibody recognizes α-tubulin at approximately 50 kDa.

WARNING This product is not for human or veterinary use.