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Cayman 5(S)-HEPE
List Price
$460.00
Your Price
$460.00
Cayman 5(S)-HEPE - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-32210-100
MFG.PART:
32210-100
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
5(S)-HEPE is an active metabolite of eicosapentaenoic acid (EPA; Item Nos. | | ). It is formed from EPA by 5-lipoxygenase (5-LO). 5(S)-HEPE is an agonist of g protein-coupled receptor 119 (GPR119). It increases cAMP accumulation in CHO-K1 cells expressing human GPR119 when used at a concentration of 10 µM. 5(S)-HEPE increases glucose-induced insulin secretion from MING6 insulinoma pancreatic islets and glucagon-like peptide 1 (GLP-1) secretion from HuTu 80 adenocarcinoma cells when used at a concentration of 10 µM. Serum levels of 5(S)-HEPE are elevated in patients with hyperlipidemia.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5S- hydroxy- 6E,8Z,11Z,14Z,17Z- eicosapentaenoic acid
CAS Number
92008-51-0
Molecular Formula
C20H30O3
Formula Weight
318.5
Purity
≥98%
Formulation
A solution in ethanol
Solubility
- 0.1 M Na2CO3: 2 mg/mL
- DMF: Miscible
- DMSO: Miscible
- Ethanol: Miscible
- PBS pH 7.2: 0.8 mg/mL
λmax
236 nm
SMILES
CC/C=C\C/C=C\C/C=C\C/C=C\C=C/[C@@H](O)CCCC(=O)O
InChi Code
InChI=1S/C20H30O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h3-4,6-7,9-10,12-14,16,19,21H,2,5,8,11,15,17-18H2,1H3,(H,22,23)/b4-3-,7-6-,10-9-,13-12-,16-14+/t19-/m1/s1
InChi Key
FTAGQROYQYQRHF-GHWNLOBHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-32210-100 |
|---|---|
| Supplier Part Number | 32210-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 92008-51-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |