Cayman CD79a (C-Term) Rabbit Monoclonal Antibody (Clone RM297)

CD79a is a member of the heterodimeric signal transduction component of the B cell receptor (BCR) complex that is encoded by CD79A/MB-1 in humans. It is composed of a disulfide-linked extracellular domain, a transmembrane region, and a cytoplasmic tail containing an immunoreceptor tyrosine-based activation motif that facilitates intracellular signaling.^, CD79a is expressed exclusively in B cells and B cell progenitors, and is commonly used as a B cell marker. It is co-expressed at the cell surface with CD79b and immunoglobulins of all isotypes as the mature BCR complex. Mutations in CD79A/MB-1 have been found in patients with autosomal recessive agammaglobulinemia. Caymans CD79a (C-Term) Rabbit Monoclonal Antibody (Clone RM297) can be used for immunohistochemistry (IHC) and Western blot (WB) applications.

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