Cayman CEA Rabbit Monoclonal Antibody (Clone RM326)

Carcinoembryonic antigen (CEA) is a glycoprotein and member of the immunoglobulin (Ig) superfamily with a role in cell adhesion.^,, It is composed of an N-terminal Ig variable domain-like (IgV-like) domain, six Ig constant 2-like (IgC2-like) domains, and a glycosylphosphatidylinositol (GPI) anchor that is attached to the cell membrane. CEA is expressed during fetal development but is absent by birth and is not present in adults. However, CEA is expressed by human colon carcinomas where it functions as a ligand for E-selectin and L-selectin that is essential to cancer metastasis. Levels of CEA are positively correlated with risk of recurrence and death in patients with non-small cell lung cancer (NSCLC). Cayman’s CEA Rabbit Monoclonal Antibody (Clone RM326) can be used for ELISA, immunohistochemistry (IHC), and Western blot (WB) applications.

WARNING This product is not for human or veterinary use.