Cayman Polyethylene Glycol Rabbit Monoclonal Antibody - Biotinylated (Clone RM105)

Polyethylene glycols (PEGs) are synthetic and hydrophilic polymers.^, They are linear or branched and contain a reactive end group, such as acrylate, methacrylate, dibenzocyclooctynol, or vinyl sulfonate, for covalent attachment to macromolecules or linkers. The opposite end group of PEGs is commonly a methyl group (methoxy PEG), however, hydroxy, amino, butoxy, and tert-butoxy end groups have also been used. PEGs are non-toxic and are commonly used to prolong the in vivo circulation time of pharmaceutical agents. Free PEGs are non-immunogenic but become immunogenic when conjugated to a drug delivery nanosystem (DDS) or a macromolecule. Immunogenicity of PEGs varies based on polymer length and branching, end group composition, and chemical nature of the PEG acceptor structure. Cayman’s Polyethylene Glycol Rabbit Monoclonal Antibody - Biotinylated (Clone RM105) can be used for ELISA, immunohistochemistry (IHC), and Western blot (WB) applications. The antibody recognizes PEGs containing a methoxy end group.

WARNING This product is not for human or veterinary use.