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Cayman mL-230
List Price $90.00 Your Price $90.00
Cayman mL-230 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-32552-1
MFG.PART: 32552-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
mL-230 is an inhibitor of ATP-binding cassette family g member 2 (ABCG2). It selectively inhibits JC-1 efflux in Ig-MXP3 cells overexpressing ABCG2 over Jurkat cells overexpressing ABCB1 (IC50s = 0.13 and 4.65 µM, respectively). mL-230 enhances inhibition of IGROV-1/T8 ovarian cancer cell colony formation induced by topotecan (Item No. ). Intratumoral injection of mL-230 (100 nM) and topotecan reduces tumor size in an IGROV-1/T8 mouse xenograft model.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-furanyl[4-
CAS Number
1776055-05-0
Synonyms
- CID-44640177
Molecular Formula
C25H21N5O3
Formula Weight
439.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMSO: soluble
λmax
285, 296 nm
SMILES
O=C(N1CCN(CC1)C2=CC(C3=CC=CO3)=NC4=CC(C5=CC=CC=C5)=NN42)C6=COC=C6
InChi Code
InChI=1S/C25H21N5O3/c31-25(19-8-14-32-17-19)29-11-9-28(10-12-29)24-16-21(22-7-4-13-33-22)26-23-15-20(27-30(23)24)18-5-2-1-3-6-18/h1-8,13-17H,9-12H2
InChi Key
LRPGMVPQQLBMNE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-32552-1 |
|---|---|
| Supplier Part Number | 32552-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1776055-05-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |