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Cayman 15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2α
List Price
$107.00
Your Price
$107.00
Cayman 15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2α - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-32791-1
MFG.PART:
32791-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2α (15-(6-nitroxyhexanoyl)-17-phenyl trinor PGF2α) is a nitric oxide-donating derivative of 17-phenyl trinor PGF2α (Item No. ). It increases cGMP levels in rabbit aqueous humor and iris ciliary body when topically administered at a concentration of 0.042%. Topical administration of 15-(6-nitroxylhexanoyl)-17-phenyl trinor PGF2α (0.14%) reduces intraocular hypertension (IOP) in a rabbit model of hypertonic saline-induced transient ocular pressure. It also reduces IOP in a cynomolgus monkey model of laser-induced ocular hypertension when administered topically at a concentration of 0.042%.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
6-(nitrooxy)- hexanoic acid, (1S,2E)-3- [(1R,2R,3S, 5R)-2-[(2Z)-7- (ethylamino)- 7-oxo-2- hepten-1-yl]- 3,5-dihydroxy cyclopentyl]- 1-(2-phenyl ethyl)-2- propen-1-yl ester
CAS Number
1194396-71-8
Synonyms
- 15-(6-nitroxyhexanoyl)-17-phenyl trinor PGF2α
- 15-(6-nitroxyhexanoyl)-Bimatoprost
- NCX 470
Molecular Formula
C31H46N2O8
Formula Weight
574.7
Purity
≥98%
Formulation
A solution in ethanol
Solubility
- DMSO: 10 mg/mL
- Ethanol: 10 mg/mL
SMILES
O[C@@H]1C[C@H](O)[C@H](C/C=C\CCCC(NCC)=O)[C@H]1/C=C/[C@H](CCC2=CC=CC=C2)OC(CCCCCO[N+]([O-])=O)=O
InChi Code
InChI=1S/C31H46N2O8/c1-2-32-30(36)16-10-4-3-9-15-26-27(29(35)23-28(26)34)21-20-25(19-18-24-13-7-5-8-14-24)41-31(37)17-11-6-12-22-40-33(38)39/h3,5,7-9,13-14,20-21,25-29,34-35H,2,4,6,10-12,15-19,22-23H2,1H3,(H,32,36)/b9-3-,21-20+/t25-,26+,27+,28-,29+/m0/s1
InChi Key
NTQMJNDRYSYWNJ-BPXWCPHMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 1 year
| SKU | CAYM-32791-1 |
|---|---|
| Supplier Part Number | 32791-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 1194396-71-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |