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Cayman MPC-6827 (hydrochloride)
List Price $63.00 Your Price $63.00
Cayman MPC-6827 (hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-32872-1
MFG.PART: 32872-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
MPC-6827 is an inhibitor of tubulin polymerization with anticancer activity., It inhibits tubulin polymerization in a cell-free assay when used at concentrations of 0.5, 5, and 50 µM, as well as in A549 cells when used at a concentration of 10 nM. MPC-6827 induces apoptosis in T47D, HCT116, and SNU-398 cancer cells (EC50s = 2, 3, and 2 nM, respectively). In vivo, MPC-6827 (2.5-10 mg/kg) reduces tumor growth in MX-1, OVCAR-3, MIA PaCa-2, MCF-7, HT-29, and MDA-MB-435 mouse xenograft models.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(4-methoxy
CAS Number
917369-31-4
Synonyms
- Verubulin
Molecular Formula
C17H17N3O • HCl
Formula Weight
315.8
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMSO: 100 mm
- Water: 100 mm
λmax
223, 334 nm
SMILES
COC(C=C1)=CC=C1N(C)C2=C3C=CC=CC3=NC(C)=N2.Cl
InChi Code
InChI=1S/C17H17N3O.ClH/c1-12-18-16-7-5-4-6-15(16)17(19-12)20(2)13-8-10-14(21-3)11-9-13;/h4-11H,1-3H3;1H
InChi Key
VYUWDIKZJLOZJL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-32872-1 |
|---|---|
| Supplier Part Number | 32872-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 917369-31-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |