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Cayman Lu AA33810
List Price $530.00 Your Price $530.00
Cayman Lu AA33810 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-32913-25
MFG.PART: 32913-25
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Lu AA33810 is an antagonist of neuropeptide Y (NPY) receptor Y5 (Ki = 1.5 nM for the human receptor).1 It is selective for Y5 over Y1, Y2, and Y4 (Kis = >10 µM for all in HEK293 membranes expressing rat receptors). Lu AA33810 also binds the serotonin (5-HT) receptor subtypes 5-HT1A and 5-HT2B (Kis = 478 and 247 nM, respectively). It inhibits NPY-induced calcium mobilization and cAMP accumulation in COS-7 and HEK293 cells expressing the rat Y5 receptor, respectively, in a concentration-dependent manner. Lu AA33810 (10 mg/kg) increases social interaction time in a social exploration test, as well as decreases immobility time in the forced swim test, in rats, indicating anxiolytic- and antidepressant-like activities, respectively.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[[trans-4-
CAS Number
304008-29-5
Molecular Formula
C19H25N3O2S3
Formula Weight
423.6
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMSO: 100 mm
λmax
225, 244, 255, 363 nm
SMILES
CS(NC[C@@H](CC1)CC[C@H]1NC2=NC3=C(S2)CCSC4=CC=CC=C34)(=O)=O
InChi Code
InChI=1S/C19H25N3O2S3/c1-27(23,24)20-12-13-6-8-14(9-7-13)21-19-22-18-15-4-2-3-5-16(15)25-11-10-17(18)26-19/h2-5,13-14,20H,6-12H2,1H3,(H,21,22)/t13-,14-
InChi Key
UWSBTSAJZMIHBL-HDJSIYSDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-32913-25 |
|---|---|
| Supplier Part Number | 32913-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 304008-29-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |