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Cayman RU-24969 (succinate)
List Price $142.00 Your Price $142.00
Cayman RU-24969 (succinate) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-33142-10
MFG.PART: 33142-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
RU-24969 is an agonist of the serotonin (5-HT) receptor subtypes 5-HT1A and 5-HT1B. It binds to 5-HT1A and 5-HT1B receptors (IC50s = 9.5 and 6.6 nM, respectively) and is selective for these receptors over 5-HT2 receptors in cell-free assays (IC50 = 5,120 nM). RU-24969 inhibits tritium efflux induced by the 5-HT antagonist methiothepin (Item No. ) in tritium-preloaded rat frontal cortex slices (PA2 = 6.27). In vivo, RU-24969 (3 mg/kg) potentiates cocaine-induced increases in nucleus accumbens dopamine levels, as well as the reinforcing effects of cocaine self-administration, in rats.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-methoxy-3-
CAS Number
66611-27-6
Molecular Formula
C14H16N2O • 1/2C4H6O4
Formula Weight
287.3
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: slightly soluble
- DMSO: slightly soluble
- Ethanol: slightly soluble
- PBS (pH 7.2): 1 mg/mL
λmax
223, 264 nm
SMILES
O=C(CCC(O)=O)O.COC1=CC2=C(NC=C2C3=CCNCC3)C=C1.COC4=CC5=C(NC=C5C6=CCNCC6)C=C4
InChi Code
InChI=1S/2C14H16N2O.C4H6O4/c2*1-17-11-2-3-14-12(8-11)13(9-16-14)10-4-6-15-7-5-10;5-3(6)1-2-4(7)8/h2*2-4,8-9,15-16H,5-7H2,1H3;1-2H2,(H,5,6)(H,7,8)
InChi Key
BNYJLRQAWCQJOM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33142-10 |
|---|---|
| Supplier Part Number | 33142-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 66611-27-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |