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Cayman Isoguvacine (hydrochloride)
List Price
$36.00
Your Price
$36.00
Cayman Isoguvacine (hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-33143-10
MFG.PART:
33143-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Isoguvacine is a GABAA receptor agonist. It binds to rat synaptic cortical membranes (Ki = 55 nM) and activates α1β2γ2S, α2β2γ2S, α3β2γ2S, α5β2γ2S, and ρ1 subunit-contanining GABAA receptors in a FLIPR assay (EC50s = 13, 4.5, 5.6, 0.78, and 3.1 µM, respectively). It inhibits CA1 population spikes in rat hippocampal slices (EC50 = 13 µM) and high potassium/low magnesium-induced seizures in rat pups., Chronic administration of isoguvacine (2 mg/kg) improves tactile over-reactivity, anxiety-like behaviors, and social impairments in mouse models of autism spectrum disorder (ASD).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1,2,3,6-tetra
CAS Number
68547-97-7
Molecular Formula
C6H9NO2 • HCl
Formula Weight
163.6
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMSO: 1 mg/mL
- PBS (pH 7.2): 10 mg/mL
SMILES
O=C(C1=CCNCC1)O.Cl
InChi Code
InChI=1S/C6H9NO2.ClH/C8-6(9)5-1-3-7-4-2-5;/h1,7H,2-4H2,(H,8,9);1H
InChi Key
SUWREQRNTXCCBL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33143-10 |
|---|---|
| Supplier Part Number | 33143-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 68547-97-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |