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Cayman Panaxadiol
List Price $204.00 Your Price $204.00
Cayman Panaxadiol - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-33233-10
MFG.PART: 33233-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Panaxadiol is a triterpenoid sapogenin that has been found in P. ginseng and has diverse biological activities.,,, It inhibits the growth of HepG2 human hepatoma, A549 lung, MCF-7 breast, and HCT116 colon cancer cells (IC50s = 63.20, 40.88, 61.96, and 92.53 µM, respectively). Panaxadiol (30 mg/kg) reduces tumor growth in an HCT116 mouse xenograft model. It inhibits hepatitis B virus (HBV) DNA replication in HepG 2.2.15 cells with an IC50 value of 148.15 µM. Panaxadiol (50 mg/kg) also decreases the escape latency in the Morris water maze (MWM) in an APP/PS1 mouse model of Alzheimers disease.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
20R,25-epoxy-
CAS Number
19666-76-3
Synonyms
- NSC 308879
- 20(R)-Panaxadiol
Molecular Formula
C30H52O3
Formula Weight
460.7
Purity
≥98%
Formulation
A crystalline solid
Solubility
- Chloroform: 10 mg/mL
- Ethanol: 0.25 mg/mL
SMILES
C[C@]12[C@]3([C@@]([C@@H](C[C@]1([H])[C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])CC2)C)O)([H])[C@]([C@@]5(OC(C)(CCC5)C)C)([H])CC3)C
InChi Code
InChI=1S/C30H52O3/c1-25(2)13-9-14-30(8,33-25)19-10-16-29(7)24(19)20(31)18-22-27(5)15-12-23(32)26(3,4)21(27)11-17-28(22,29)6/h19-24,31-32H,9-18H2,1-8H3/t19-,20+,21-,22+,23-,24-,27-,28+,29+,30+/m0/s1
InChi Key
PVLHOJXLNBFHDX-XHJPDDKBSA-N
Origin
Plant/Panax ginseng
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33233-10 |
|---|---|
| Supplier Part Number | 33233-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 19666-76-3 |
| Energy Star | No |
| Green | No |
| Controlled | N |