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Cayman Phenytoin-d10


Product Description
Phenytoin-d10 is intended for use as an internal standard for the quantification of phenytoin (Item No. ) by GC- or LC-MS. Phenytoin is an anticonvulsant agent and active metabolite of fosphenytoin (Item No. ). Phenytoin is formed from fosphenytoin by tissue phosphatases. It inhibits neuronal voltage-gated sodium channels in a voltage-dependent manner. Phenytoin reduces the neuronal firing frequency and decreases the amplitude of excitatory post-synaptic potentials (EPSPs) in electrically stimulated rat corticostriatal slices (EC50s = 42.8 and 33.5 µM, respectively). It protects against seizures induced by maximal electroshock (MES) in mice (ED50 = 10 mg/kg). Formulations containing phenytoin have been used in the treatment of tonic-clonic seizures and status epilepticus.
WARNING This product is not for human or veterinary use.
Technical Information
- 5,5-Diphenylhydantoin-d10
- DMSO: slightly soluble
- Methanol: slightly soluble
Shipping & Storage Information
| SKU | CAYM-33245-1 |
|---|---|
| Supplier Part Number | 33245-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 65854-97-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |

