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Cayman rac-Tolterodine-d14 (tartrate)
List Price $214.00 Your Price $214.00
Cayman rac-Tolterodine-d14 (tartrate) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-33281-1
MFG.PART: 33281-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
rac-Tolterodine-d14 is intended for use as an internal standard for the quantification of tolterodine (Item No. ) by GC- or LC-MS. Tolterodine is an antagonist of muscarinic acetylcholine receptors (Kis = 1.4, 2.7, 3.6, 3.1, and 2.2 nM for M1-5 receptors, respectively). It reduces intracellular calcium mobilization induced by carbachol (carbamoylcholine; Item No. ) in bladder smooth muscle cells and submandibular gland cells isolated from cynomolgus monkeys (Kis = 3.16 and 2 nM, respectively). Tolterodine inhibits volume-induced bladder contractions and oxotremorine-induced salivation in rats (ID50s = 0.025 and 0.12 mg/kg, respectively). Formulations containing tolterodine have been used in the treatment of overactive bladder.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[3-[bis[1-
Synonyms
- PNU 200583E-d14
Molecular Formula
C22H17D14NO • C4H6O6
Formula Weight
489.7
Purity
≥99% deuterated forms (d1-d14)
Formulation
A solid
Solubility
- DMSO: soluble
- Methanol: soluble
SMILES
[2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])N(C(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])CCC(C1=CC=CC=C1)C2=C(C=CC(C)=C2)O.OC(C(C(O)=O)O)C(O)=O
InChi Code
InChI=1S/C22H31NO.C4H6O6/c1-16(2)23(17(3)4)14-13-20(19-9-7-6-8-10-19)21-15-18(5)11-12-22(21)24;5-1(3(7)8)2(6)4(9)10/h6-12,15-17,20,24H,13-14H2,1-5H3;1-2,5-6H,(H,7,8)(H,9,10)/i1D3,2D3,3D3,4D3,16D,17D;
InChi Key
TWHNMSJGYKMTRB-HHJIGIPXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33281-1 |
|---|---|
| Supplier Part Number | 33281-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |