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Cayman CP21
List Price $40.00 Your Price $40.00
Cayman CP21 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-33318-1
MFG.PART: 33318-1
UNSPSC: 12352200
Manufacturer: Cayman


Product Description
CP21 is an iron chelator that binds to iron in a 3:1 (ligand:iron) ratio. It is active against P. falciparum when used at concentrations of 10 and 100 µM. CP21 inhibits production of prostaglandin I2 (PGI2; Item No. ) induced by epinephrine, arachidonic acid (Item Nos. | | ), or A23187 (Item No. ) in isolated rat aortic rings with IC50 values of 1.3, 1.3, and 1.4 mm, respectively. It inhibits glutamate-induced oxytosis, as well as decreases iodoacetic acid-induced cytotoxicity in an in vitro model of ischemia, in HT22 mouse hippocampal cells (EC50s = 13 and 9.5 µM, respectively). CP21 (200 mg/kg) increases the excretion of iron, but not copper, zinc, calcium, or magnesium, in rabbits.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-ethyl-3- hydroxy-2-methyl- 4(1H)-pyridinone
CAS Number
30652-12-1
Molecular Formula
C8H11NO2
Formula Weight
153.2
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 1 mg/mL
- DMSO: 1 mg/mL
- Ethanol: 10 mg/mL
- Ethanol:PBS (pH 7.2) (1:4): 0.20 mg/mL
λmax
218, 285 nm
SMILES
O=C1C=CN(CC)C(C)=C1O
InChi Code
InChI=1S/C8H11NO2/c1-3-9-5-4-7(10)8(11)6(9)2/h4-5,11H,3H2,1-2H3
InChi Key
LCWFIBYPSAWVLI-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33318-1 |
|---|---|
| Supplier Part Number | 33318-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 30652-12-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |

