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Cayman Clobetasol Propionate-d5
List Price $267.00 Your Price $267.00
Cayman Clobetasol Propionate-d5 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-33365-1
MFG.PART: 33365-1
UNSPSC: 12352200
Manufacturer: Cayman


Product Description
Clobetasol propionate-d5 is intended for use as an internal standard for the quantification of clobetasol propionate (Item No. ) by GC- or LC-MS. Clobetasol propionate is a corticosteroid. It binds to glucocorticoid receptors in a cell-free assay (IC50 = 3.17 nM) and inhibits proliferation of primary human skin fibroblasts when used at a concentration of 5 µg/mL., Topical administration of clobetasol propionate reduces croton oil-induced ear edema in mice. Formulations containing clobetasol propionate have been used in the treatment of inflammatory skin conditions.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
21-chloro-9- fluoro-11- hydroxy-16- methyl-17-(1- oxopropoxy-2,2, 3,3,3-d5)-(11β, 16β)-pregna- 1,4-diene-3,20- dione
CAS Number
2280940-18-1
Synonyms
- CCI-4725-d5
- CGP 9555-d5
- Clobetasol 17-propionate-d5
Molecular Formula
C25H27ClD5FO5
Formula Weight
472.0
Purity
≥99% deuterated forms (d1-d5)
Formulation
A solid
Solubility
- Methanol: soluble
SMILES
O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2(F)[C@@H](O)C[C@@]4(C)[C@@]3([H])C[C@H](C)[C@@]4(C(CCl)=O)OC(C([2H])([2H])C([2H])([2H])[2H])=O)=C1
InChi Code
InChI=1S/C25H32ClFO5/c1-5-21(31)32-25(20(30)13-26)14(2)10-18-17-7-6-15-11-16(28)8-9-22(15,3)24(17,27)19(29)12-23(18,25)4/h8-9,11,14,17-19,29H,5-7,10,12-13H2,1-4H3/t14-,17-,18-,19-,22-,23-,24-,25-/m0/s1/i1D3,5D2
InChi Key
CBGUOGMQLZIXBE-BFHSNLKKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33365-1 |
|---|---|
| Supplier Part Number | 33365-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2280940-18-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |

