We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Cayman 7-Chlorokynurenic Acid
List Price $363.00 Your Price $363.00
Cayman 7-Chlorokynurenic Acid - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-33408-50
MFG.PART: 33408-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
7-Chlorokynurenic acid is an NMDA receptor antagonist.1 It selectively binds to the NMDA receptor glycine-binding site (IC50 = 0.56 µM) over the NMDA-, quisqualate-, and kainate-binding sites (IC50s = 169, 153, and >1,000 µM, respectively). Intra-dorsal hippocampal administration of 7-chlorokynurenic acid (3.2 µg per side) increases the number of errors in a three-panel runway test of working memory, an effect that can be blocked by the NMDA glycine-site co-agonist D-serine (Item No. 31197).2 It also induces antidepressant-like activity in the forced swim test, novelty-suppressed feeding test, and a foot shock-based learned helplessness test in mice when administered at doses of 0.1 and 1 mg/kg.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
7-chloro-4-
CAS Number
18000-24-3
Synonyms
- 7-CKA
- 7-CTKA
- 7-chloro KYNA
- NSC 149792
Molecular Formula
C10H6ClNO3
Formula Weight
223.6
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMSO: slightly soluble
- Ethanol: slightly soluble
λmax
223, 250, 340 nm
SMILES
O=C(C1=CC(O)=C2C=CC(Cl)=CC2=N1)O
InChi Code
InChI=1S/C10H6ClNO3/c11-5-1-2-6-7(3-5)12-8(10(14)15)4-9(6)13/h1-4H,(H,12,13)(H,14,15)
InChi Key
UAWVRVFHMOSAPU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33408-50 |
|---|---|
| Supplier Part Number | 33408-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 18000-24-3 |
| Energy Star | No |
| Green | No |
| Controlled | N |