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Cayman Imidazole Propionate
List Price $46.00 Your Price $46.00
Cayman Imidazole Propionate - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-33458-50
MFG.PART: 33458-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Imidazole propionate is a metabolite of histidine.1 It is formed from histidine via a urocanate intermediate in gut microbiota by urocanate reductase (urdA). Imidazole propionate (100 µM) decreases protein levels of insulin receptor substrate 1 (IRS-1), IRS-2, and phosphorylated Akt and increases levels of the mTORC1 activation marker phosphorylated p70 ribosomal S6 kinase (p70S6K) in primary mouse hepatocytes. It induces deficits in glucose tolerance in germ-free and conventionally raised mice when administered at doses of 500 and 100 µg/animal, respectively. It also prevents reductions in blood glucose levels induced by metformin (Item No. 13118) in mice.2 Plasma levels of imidazole propionate are increased in patients with type 2 diabetes.1,2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1H-imidazole-
CAS Number
1074-59-5
Synonyms
- Deamino-histidine
- Imidazolepropionic Acid
- NSC 66737
Molecular Formula
C6H8N2O2
Formula Weight
140.1
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- PBS (pH 7.2): 5 mg/mL
SMILES
O=C(CCC1=CN=CN1)O
InChi Code
InChI=1S/C6H8N2O2/c9-6(10)2-1-5-3-7-4-8-5/h3-4H,1-2H2,(H,7,8)(H,9,10)
InChi Key
ZCKYOWGFRHAZIQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33458-50 |
|---|---|
| Supplier Part Number | 33458-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1074-59-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |