We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Cayman Batabulin (sodium salt)
List Price $168.00 Your Price $168.00
Cayman Batabulin (sodium salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-33487-10
MFG.PART: 33487-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Batabulin is an inhibitor of tubulin polymerization. It covalently binds to cysteine 239 (Cys239) of the β1, β2, and β4 tubulin isotypes and inhibits polymerization of bovine brain tubulin (IC50 = 2 µM) in cell-free assays. Batabulin (30, 100, and 300 nM) induces cytoskeletal collapse and cell cycle arrest at the g2/M phase in MCF-7 breast cancer cells. It is cytotoxic against a panel of drug-sensitive and -resistant cancer cell lines (IC50s = 11-165 nM). Batabulin (40 mg/kg) reduces tumor volume in CCRF CEM lymphoblastic leukemia and CEM/VBL100 multidrug-resistant lymphoblastic leukemia mouse xenograft models.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2,3,4,5,6-
CAS Number
195533-98-3
Synonyms
- T138067
Molecular Formula
C13H6F6NO3S • Na
Formula Weight
393.2
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
- Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/mL
λmax
235 nm
SMILES
O=S([N-]C1=CC=C(C(F)=C1)OC)(C2=C(F)C(F)=C(F)C(F)=C2F)=O.[Na+]
InChi Code
InChI=1S/C13H6F6NO3S.Na/c1-23-7-3-2-5(4-6(7)14)20-24(21,22)13-11(18)9(16)8(15)10(17)12(13)19;/h2-4H,1H3;/q-1;+1
InChi Key
UWPXRVDIKGZQQW-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33487-10 |
|---|---|
| Supplier Part Number | 33487-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 195533-98-3 |
| Energy Star | No |
| Green | No |
| Controlled | N |