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Cayman mL-145
List Price $69.00 Your Price $69.00
Cayman mL-145 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-33534-1
MFG.PART: 33534-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
mL-145 is an antagonist of g protein-coupled receptor 35 (GPR35). It inhibits β-arrestin recruitment induced by the GPR35 agonists zaprinast (Item No. ), cromolyn (Item No. ), and pamoic acid (Item No. ) in HEK293 cells expressing the human receptor (EC50s = 26, 22, and 8.3 nM, respectively). mL-145 inhibits constitutive and agonist-mediated D-myo-inositol-1-phosphate (IP1) accumulation in cells expressing human, but not rat, GPR35 in a concentration-dependent manner.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-hydroxy-4-
CAS Number
1164500-72-4
Molecular Formula
C24H22N2O5S2
Formula Weight
482.6
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: 50 mg/mL, sonicated
SMILES
OC(C=C1NC(CCCN2C(S/C(C2=O)=C\C(C)=C\C3=CC=CC=C3)=S)=O)=C(C=C1)C(O)=O
InChi Code
InChI=1S/C24H22N2O5S2/c1-15(12-16-6-3-2-4-7-16)13-20-22(29)26(24(32)33-20)11-5-8-21(28)25-17-9-10-18(23(30)31)19(27)14-17/h2-4,6-7,9-10,12-14,27H,5,8,11H2,1H3,(H,25,28)(H,30,31)/b15-12+,20-13-
InChi Key
COFMYJWNXSFLKQ-QIROLCGISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33534-1 |
|---|---|
| Supplier Part Number | 33534-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1164500-72-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |