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Cayman RBN-2397
List Price $83.00 Your Price $83.00
Cayman RBN-2397 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-33558-1
MFG.PART: 33558-1
UNSPSC: 12352200
Manufacturer: Cayman


Product Description
RBN-2397 is an inhibitor of poly(ADP-ribose) polymerase 7 (PARP7). It stabilizes wild-type PARP7 levels, but not levels of the catalytically inactive mutant PARP7H532A, in COS-1 cells expressing wild-type or mutant PARP7, respectively, when used at a concentration of 100 nM. RBN-2397 (100 nM) also decreases wild-type PARP7 catalytic activity in the same cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-[[(1S)-1- methyl-2-[3- oxo-3-[4-[5- (trifluoro methyl)-2- pyrimidinyl]-1- piperazinyl] propoxy]ethyl] amino]-4- (trifluoro methyl)-3(2H)- pyridazinone
CAS Number
2381037-82-5
Molecular Formula
C20H23F6N7O3
Formula Weight
523.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 1 mg/mL
- DMSO: 1 mg/mL
λmax
221, 254 nm
SMILES
FC(F)(C1=C(C=NNC1=O)N[C@@H](C)COCCC(N2CCN(C3=NC=C(C(F)(F)F)C=N3)CC2)=O)F
InChi Code
InChI=1S/C20H23F6N7O3/c1-12(30-14-10-29-31-17(35)16(14)20(24,25)26)11-36-7-2-15(34)32-3-5-33(6-4-32)18-27-8-13(9-28-18)19(21,22)23/h8-10,12H,2-7,11H2,1H3,(H2,30,31,35)/t12-/m0/s1
InChi Key
UQZCQKXJAXKZQH-LBPRGKRZSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33558-1 |
|---|---|
| Supplier Part Number | 33558-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2381037-82-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |

