Cayman Para-Fluoro Phenethyl 4-Anpp (Hydrochloride); Size- 1 Mg

Name: Cayman Para-Fluoro Phenethyl 4-Anpp (Hydrochloride); Size- 1 Mg
SKU: CAYM-33565-1
Price: 117.00 USD

List Price $117.00 Your Price $117.00

Cayman Para-Fluoro Phenethyl 4-Anpp (Hydrochloride); Size- 1 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)

NETA PART: CAYM-33565-1

MFG.PART: 33565-1

UNSPSC: 12352200

Manufacturer: Cayman

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Description

Product Description

Pituitary adenylate cyclase-activating peptide (PACAP) (6-38) is a PACAP receptor antagonist with IC₅₀ values of 30, 600, and 40 nM, respectively for rat PAC₁, rat VPAC₁, and human VPAC₂ recombinant receptors expressed in CHO cells. It binds to PACAP receptors in rat brain membrane (IC₅₀ = 39.14 nM) and to SH-SY5Y and SK-N-MC human neuroblastoma and T47D human breast cancer cells (IC₅₀s = 2.9, 129, and 227 nM, respectively).^, In vivo, in newborn pigs, PACAP (6-38) (10 μM) inhibits vasodilation of pial arterioles induced by PACAP (1-38) (Item No. ), the full-length peptide. It also inhibits decreased food intake and reduced body weight in rats induced by cocaine- and amphetamine-regulated transcript peptides (CARTp) following intracerebroventricular administration of 0.3-3 mol per animal doses.

WARNING This product is not for human or veterinary use.

Technical Information

Formal Name

L-phenylalanyl-L-threonyl-L-α-aspartyl-L-seryl-L-tyrosyl-L-seryl-L-arginyl-L-tyrosyl-L-arginyl-L-lysyl-L-glutaminyl-L-methionyl-L-alanyl-L-valyl-L-lysyl-L-lysyl-L-tyrosyl-L-leucyl-L-alanyl-L-alanyl-L-valyl-L-leucylglycyl-L-lysyl-L-arginyl-L-tyrosyl-L-lysyl-L-glutaminyl-L-arginyl-L-valyl-L-lysyl-L-asparaginyl-L-lysinamide, trifluoroacetate salt

Synonyms

Pituitary Adenylate Cyclase-activating Peptide (6-38)

Molecular Formula

C₁₈₂H₃₀₀N₅₆O₄₅S • XCF₃COOH

Formula Weight

4024.7

Purity

≥95%

Formulation

A lyophilized powder

Solubility

Water: 1 mg/ml

SMILES

NC([C@H](CCCCN)NC([C@H](CC(N)=O)NC([C@H](CCCCN)NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](CCCCN)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC(CNC([C@H](CC(C)C)NC([C@H](C(C)C)NC([C@@H](NC([C@@H](NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](C(C)C)NC([C@@H](NC([C@@H](NC([C@H](CCC(N)=O)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@@H](NC([C@H](CO)NC([C@@H](NC([C@@]([C@@H](C)O)([H])NC([C@@H](N[H])CC1=CC=CC=C1)=O)=O)CC(O)=O)=O)=O)CC2=CC=C(O)C=C2)=O)=O)=O)CC3=CC=C(O)C=C3)=O)=O)=O)=O)CCSC)=O)C)=O)=O)=O)=O)CC4=CC=C(O)C=C4)=O)=O)C)=O)C)=O)=O)=O)=O)=O)=O)CC5=CC=C(O)C=C5)=O)=O)=O)=O)=O)=O)=O)=O.FC(F)(C(O)=O)F

InChi Code

InChI=1S/C182H300N56O45S.C2HF3O2/c1-95(2)83-128(152(257)207-92-141(249)211-115(40-20-27-72-184)154(259)215-122(47-34-79-204-180(197)198)161(266)226-130(86-105-50-58-109(242)59-51-105)167(272)217-117(42-22-29-74-186)156(261)220-125(66-68-138(191)246)163(268)216-124(49-36-81-206-182(201)202)165(270)237-145(99(9)10)176(281)224-120(45-25-32-77-189)160(265)230-134(90-140(193)248)171(276)212-114(147(194)252)39-19-26-71-183)231-177(282)144(98(7)8)236-149(254)101(12)208-148(253)100(11)210-166(271)129(84-96(3)4)225-169(274)132(88-107-54-62-111(244)63-55-107)228-159(264)118(43-23-30-75-187)214-157(262)119(44-24-31-76-188)223-175(280)143(97(5)6)235-150(255)102(13)209-153(258)127(70-82-284-15)222-164(269)126(67-69-139(192)247)221-155(260)116(41-21-28-73-185)213-158(263)121(46-33-78-203-179(195)196)218-168(273)131(87-106-52-60-110(243)61-53-106)227-162(267)123(48-35-80-205-181(199)200)219-173(278)136(93-239)233-170(275)133(89-108-56-64-112(245)65-57-108)229-174(279)137(94-240)234-172(277)135(91-142(250)251)232-178(283)146(103(14)241)238-151(256)113(190)85-104-37-17-16-18-38-104;3-2(4,5)1(6)7/h16-18,37-38,50-65,95-103,113-137,143-146,239-245H,19-36,39-49,66-94,183-190H2,1-15H3,(H2,191,246)(H2,192,247)(H2,193,248)(H2,194,252)(H,207,257)(H,208,253)(H,209,258)(H,210,271)(H,211,249)(H,212,276)(H,213,263)(H,214,262)(H,215,259)(H,216,268)(H,217,272)(H,218,273)(H,219,278)(H,220,261)(H,221,260)(H,222,269)(H,223,280)(H,224,281)(H,225,274)(H,226,266)(H,227,267)(H,228,264)(H,229,279)(H,230,265)(H,231,282)(H,232,283)(H,233,275)(H,234,277)(H,235,255)(H,236,254)(H,237,270)(H,238,256)(H,250,251)(H4,195,196,203)(H4,197,198,204)(H4,199,200,205)(H4,201,202,206);(H,6,7)/t100-,101-,102-,103+,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,143-,144-,145-,146-;/m0./s1

InChi Key

VUTZKHJLSOPDFM-IKLXZCEOSA-N

Shipping & Storage Information

Storage

-20°C

Shipping

Room Temperature in continental US; may vary elsewhere

Stability

≥ 4 years

Specifications

More Information
SKU	CAYM-33565-1
Featured	No
Supplier Part Number	33565-1
UM	EA
UNSPSC	12352200
Manufacturer	Cayman
MSDS URL	Click here
Temperature	-20
Refrigerated-Frozen	Refrigerated
CountryOfOrigin	United States
ProductLine	CAYM
Qty	1
MinOrderQty	1
Weight	7.000000
Lead Time	2
Hazardous	N
Energy Star	No
Green	No
ACT Ecolabel	No
Controlled	N

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NETA PART NO.	Quantity

Cayman Para-Fluoro Phenethyl 4-Anpp (Hydrochloride); Size- 1 Mg

Product Description

Technical Information

Shipping & Storage Information

Product Title