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Cayman IMP-1700
List Price $173.00 Your Price $173.00
Cayman IMP-1700 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-33724-10
MFG.PART: 33724-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
IMP-1700 is an inhibitor of bacterial DNA repair. It potentiates the activity of the quinolone antibiotic ciprofloxacin (Item No. ) against methicillin-resistant S. aureus (MRSA) with a combination index value of 0.7. IMP-1700 inhibits the ciprofloxacin-induced bacterial SOS response, a process that repairs DNA damage, in a reporter assay in a concentration-dependent manner. It is also active against E. coli, as well as methicillin-resistant and -sensitive S. aureus, when used alone (EC50s = 0.5, 0.21, and 3.8 µM, respectively).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-cyclopropyl-
CAS Number
1458674-25-3
Molecular Formula
C25H22F4N4O3S
Formula Weight
534.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: slightly soluble
- DMSO: slightly soluble
λmax
283 nm
SMILES
O=C(C1=CN(C2CC2)C3=CC(N4CCN(CC4)C(NC5=CC=C(C(F)(F)F)C=C5)=S)=C(C=C3C1=O)F)O
InChi Code
InChI=1S/C25H22F4N4O3S/c26-19-11-17-20(33(16-5-6-16)13-18(22(17)34)23(35)36)12-21(19)31-7-9-32(10-8-31)24(37)30-15-3-1-14(2-4-15)25(27,28)29/h1-4,11-13,16H,5-10H2,(H,30,37)(H,35,36)
InChi Key
DMUZWIXJZNKJPP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33724-10 |
|---|---|
| Supplier Part Number | 33724-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1458674-25-3 |
| Energy Star | No |
| Green | No |
| Controlled | N |