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Cayman rac-trans-4-hydroxy Glyburide
List Price $69.00 Your Price $69.00
Cayman rac-trans-4-hydroxy Glyburide - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-33752-500
MFG.PART: 33752-500
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
rac-trans-4-hydroxy Glyburide is an active metabolite of the SUR1/KIR6.2 sulfonylurea inhibitor glyburide (Item No. 15009).1,2 It is formed from glyburide by the cytochrome P450 (CYP) isoforms CYP2C8 and CYP2C9.1 rac-trans-4-hydroxy Glyburide inhibits glyburide binding to rat brain synaptosomes at the high and low affinity sites of SUR1/KIR6.2 with IC50 values of 0.95 and 100 nM, respectively.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-chloro-N-[2-
CAS Number
23155-00-2
Synonyms
- 4-trans-hydroxycyclohexyl Glyburide
- 4-trans-hydroxy Glibenclamide
Molecular Formula
C23H28ClN3O6S
Formula Weight
510.0
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMSO: slightly soluble
- Methanol: slightly soluble
SMILES
O[C@H](CC1)CC[C@@H]1NC(NS(C(C=C2)=CC=C2CCNC(C3=C(C=CC(Cl)=C3)OC)=O)(=O)=O)=O
InChi Code
InChI=1S/C23H28ClN3O6S/c1-33-21-11-4-16(24)14-20(21)22(29)25-13-12-15-2-9-19(10-3-15)34(31,32)27-23(30)26-17-5-7-18(28)8-6-17/h2-4,9-11,14,17-18,28H,5-8,12-13H2,1H3,(H,25,29)(H2,26,27,30)/t17-,18-
InChi Key
IUWSGCQEWOOQDN-IYARVYRRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33752-500 |
|---|---|
| Supplier Part Number | 33752-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 23155-00-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |