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Cayman NVS-ZP7-4
List Price $69.00 Your Price $69.00
Cayman NVS-ZP7-4 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-33773-1
MFG.PART: 33773-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
NVS-ZP7-4 is an inhibitor of the zinc transporter SLC39A7 (ZIP7). It induces apoptosis in TALL-1 human T cell acute lymphoblastic leukemia cells, an effect that can be reduced by expression of the ZIP7 point mutant ZIP7V430E. NVS-ZP7-4 (20 µM) increases endoplasmic reticulum, but not cytosolic, zinc levels in U2OS cells. It inhibits ferroptosis induced by erastin (Item No. ) in MDA-MB-231 and RCC4 cells when used at a concentration of 10 µM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-[(2S)-2-[(6-
CAS Number
2349367-89-9
Molecular Formula
C28H28FN5OS
Formula Weight
501.6
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: soluble
- Ethanol: soluble
λmax
227, 256 nm
SMILES
O=C1NC2(CCN(CC2)C[C@H](CC3=CC=CC=C3)NC4=NC5=CC=C(F)C=C5S4)C6=CC=CC=C6N1
InChi Code
InChI=1S/C28H28FN5OS/c29-20-10-11-24-25(17-20)36-27(32-24)30-21(16-19-6-2-1-3-7-19)18-34-14-12-28(13-15-34)22-8-4-5-9-23(22)31-26(35)33-28/h1-11,17,21H,12-16,18H2,(H,30,32)(H2,31,33,35)/t21-/m0/s1
InChi Key
FZOFDZMKSAUTHT-NRFANRHFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33773-1 |
|---|---|
| Supplier Part Number | 33773-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2349367-89-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |