Cayman Ornidazole-d5

Ornidazole-d₅ is intended for use as an internal standard for the quantification of ornidazole (Item No. 26818) by GC- or LC-MS. Ornidazole is an orally bioavailable 5-nitroimidazole derivative with antibacterial and antiprotozoal activities.^1,2 Ornidazole inhibits the growth of clinical isolates of B. fragilis (MICs = 0.5-5 μM) and various anaerobic bacteria when used at concentrations ranging from less than 0.1 to 3.2 μg/mL.^2,3 It also inhibits the growth of Giardia isolates (IC₅₀s = 0.01-0.47 μg/mL).⁴ Oral administration of ornidazole reduces T. vaginalis and T. foetus infection in mice and E. histolytica infection in rats with curative dose (CD₅₀) values of 37, 3, and 10 mg/kg, respectively.¹ Ornidazole (400 mg/kg per day) induces infertility in male rats within 7 days and inhibits spermatozoa binding to rat oocyte zona pellucida.^5,6

WARNING This product is not for human or veterinary use.