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Cayman EFdA
List Price $134.00 Your Price $134.00
Cayman EFdA - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-33873-1
MFG.PART: 33873-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
EFdA is a nucleoside reverse transcriptase inhibitor (NRTI). It inhibits HIV-1 reverse transcriptase via multiple mechanisms. EFdA inhibits replication of the HIV-1 strain HIV-1 IIIb, the laboratory isolate HIV NL4-3, and the clinical isolate HIV-2 EHO in MT-4 cells (EC50s = 73, 50, and 98 pM, respectively). It is also active against drug-resistant HIV with EC50 values ranging from 0.23 to 23 nM in a multinuclear activation of a galactosidase indicator (MAGI) assay. EFdA (1 and 10 mg/kg per day) prevents infection with HIV JR-CSF in humanized mice.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2′-deoxy-4′-C-
CAS Number
865363-93-5
Synonyms
- 4’Ed2FA
- 4′-ethynyl-2-fluoro-2′-Deoxyadenosine
- EFDA
- MK-8591
Molecular Formula
C12H12FN5O3
Formula Weight
293.3
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: soluble
λmax
263 nm
SMILES
FC1=NC(N)=C2C(N([C@@]3([H])C[C@H](O)[C@@](C#C)(CO)O3)C=N2)=N1
InChi Code
InChI=1S/C12H12FN5O3/c1-2-12(4-19)6(20)3-7(21-12)18-5-15-8-9(14)16-11(13)17-10(8)18/h1,5-7,19-20H,3-4H2,(H2,14,16,17)/t6-,7+,12+/m0/s1
InChi Key
IKKXOSBHLYMWAE-QRPMWFLTSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33873-1 |
|---|---|
| Supplier Part Number | 33873-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 865363-93-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |