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Cayman Prosaptide TX14(A) (trifluoroacetate salt)
List Price $184.00 Your Price $184.00
Cayman Prosaptide TX14(A) (trifluoroacetate salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-33935-1
MFG.PART: 33935-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Prosaptide TX14(A) is a peptide fragment of the neurotrophic factor prosaposin and an agonist of GPR37L1 and GPR37. It activates ERK signaling in HEK293T cells expressing GPR37L1 or GPR37 (EC50s = 5 and 7 nM, respectively) and inhibits forskolin-induced cAMP production in the same cells. Prosaptide TX14(A) (100 nM) protects primary mouse astrocytes from hydrogen peroxide-induced cell death. It reduces allodynia in a variety of rat peripheral pain models, including models of diabetic neuropathy and sciatic nerve hemiligation when administered at a dose of 4 mg/kg, as well as prevents paw allodynia induced by formalin at 1 mg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
L-threonyl-D-
Synonyms
- Prosaposin-derived 14-mer Peptide TX14(A)
Molecular Formula
C69H110N16O26 • XCF3COOH
Formula Weight
1579.7
Purity
≥98%
Formulation
A solid
Solubility
- DMF: 1 mg/mL
- DMSO: 1 mg/mL
SMILES
OC(C=C1)=CC=C1C[C@@H](C(O)=O)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](C)NC([C@H](CC(N)=O)NC([C@H](CC(N)=O)NC([C@H](CC(O)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CC(C)C)NC([C@@H](C)NC([C@@H](N)[C@H](O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C69H110N16O26.C2HF3O2/c1-13-31(7)53(66(107)80-41(23-29(3)4)61(102)82-46(69(110)111)25-37-15-17-38(88)18-16-37)83-59(100)40(20-22-50(93)94)75-58(99)39(19-21-49(91)92)76-68(109)55(36(12)87)85-57(98)34(10)73-60(101)43(26-47(70)89)78-62(103)44(27-48(71)90)79-63(104)45(28-51(95)96)81-67(108)54(32(8)14-2)84-64(105)42(24-30(5)6)77-56(97)33(9)74-65(106)52(72)35(11)86;3-2(4,5)1(6)7/h15-18,29-36,39-46,52-55,86-88H,13-14,19-28,72H2,1-12H3,(H2,70,89)(H2,71,90)(H,73,101)(H,74,106)(H,75,99)(H,76,109)(H,77,97)(H,78,103)(H,79,104)(H,80,107)(H,81,108)(H,82,102)(H,83,100)(H,84,105)(H,85,98)(H,91,92)(H,93,94)(H,95,96)(H,110,111);(H,6,7)/t31-,32-,33+,34-,35+,36+,39-,40-,41-,42-,43-,44-,45-,46-,52-,53-,54-,55-;/m0./s1
InChi Key
NWNAHGRGWGVHED-LKMBYFDSSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-33935-1 |
|---|---|
| Supplier Part Number | 33935-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |