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Cayman Shanzhiside methyl ester
List Price $41.00 Your Price $41.00
Cayman Shanzhiside methyl ester - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-34047-1
MFG.PART: 34047-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Shanzhiside methyl ester is an iridoid glycoside that has been found in L. rotata and has anti-inflammatory and antinociceptive activities.1,2 It is a glucagon-like peptide 1 receptor (GLP-1R) agonist.1 Shanzhiside methyl ester (10 µM) inhibits the release of myeloperoxidase (MPO) and elastase from isolated rat neutrophils activated by N-Formyl-Met-Leu-Phe (fMLF; Item No. 21495).2 It also inhibits LPS-induced increases in the release of IL-8 and leukotriene B4 (LTB4; Item Nos. 20110 | 10007240) from isolated rat neutrophils when used at a concentration of 10 µM. Shanzhiside methyl ester reduces L5/L6 spinal nerve ligation-induced mechanical allodynia in rats (ED50 = 40.4 µg/animal), an effect that can be reversed by the GLP-1R antagonist exendin (9-39).1
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-(β-D-gluco
CAS Number
64421-28-9
Molecular Formula
C17H26O11
Formula Weight
406.4
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
- PBS (pH 7.2): 10 mg/mL
λmax
238 nm
SMILES
COC(C1=CO[C@H]([C@@]2([H])[C@]1([H])[C@@H](C[C@@]2(O)C)O)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)=O
InChi Code
InChI=1S/C17H26O11/c1-17(24)3-7(19)9-6(14(23)25-2)5-26-15(10(9)17)28-16-13(22)12(21)11(20)8(4-18)27-16/h5,7-13,15-16,18-22,24H,3-4H2,1-2H3/t7-,8-,9+,10-,11-,12+,13-,15+,16+,17+/m1/s1
InChi Key
KKSYAZCUYVRKML-IRDZEPHTSA-N
Origin
Plant/Lamiophlomis rotata
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-34047-1 |
|---|---|
| Supplier Part Number | 34047-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 64421-28-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |